Towards an efficient read-across and grouping of nanomaterials (GRACIOUS)


The GRACIOUS project develops a highly innovative science-based framework that supports the assessment of risk posed by the ever increasing array of nanomaterials on the market and under development. The framework will streamline the process for assessing their risk by logically grouping nanomaterials thereby allowing extrapolation between (read-across) nanomaterials and reducing the need to assess exposure to and toxicity on a case by case basis.
Background: Manufacturing and functionalising materials at the nanoscale leads to a whole array of nanomaterials varying in e.g. size, morphology and surface characteristics. Due to financial, time and ethical consideration, safety testing of every unique nanomaterial for their potential adverse effects is virtually impossible. For these reasons, more efficient ways to obtain safety information are needed.
Impact: Application of the Framework will allow movement away from the case-by-case risk assessment paradigm, thereby improving the efficiency of risk analysis and decision making for safer design of quality nano-enabled products.
GRACIOUS involves first class scientists from large companies, government, small and medium enterprises and academia. These 23 partners have been actively involved in developing the existing grouping, read-across and hazard identification schemes for NMs published by industry), by policy makers  and EC funded research projects.
The University of Vienna is mainly involved in the characterization of nanomaterial physico-chemical proprieties (e.g. surface charge properties) and the investigation of transformation of nanomaterials in environmental media.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 760840.

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