Incubation experiments were conducted using artificial seawater enriched with copper, iron, lead, and zinc at various concentrations. Isotopically labeled compounds were added to trace assimilation over time. Results showed that increased copper levels exhibited the greatest toxicity, while iron enhanced symbiont activity regardless of concentration, indicating iron limitation. Lead had no detectable effect, while low zinc concentrations promoted foraminifera metabolism but higher concentrations proved toxic. Overall, the study highlights the complex interactions between heavy metals and foraminifera metabolism, shedding light on potential environmental impacts.