Mineral Surfaces: Origin and Archive of Biological Information

Current Projects EDGE | Stephan M. Krämer

New findings in the fields of microbiome research and anthropology have demonstrated that DNA fragments (so called ‘ancient DNA’ or ‘aDNA’) can survive over many millennia outside living organisms. At the same time, scientists have often speculated that the prebiotic synthesis of nucleic acids on mineral surfaces may have played an important role in the emergence of life.

The mechanisms of the synthesis and the degradation of nucleic acids on mineral surfaces, including the concomitant structural, mechanistic, thermodynamic and kinetic factors are the subject of this study.

First, the adsorption of nucleic acids and their building blocks on mineral surfaces will be studied. Then, the formation of nucleic acids from their building blocks will be investigated and the structure of the products will be clarified. Finally, the stabilization and long-term protection of nucleic acids on mineral surface will be studied. A particular focus will be the role of other organic substances that are typically found on mineral surfaces in the environment in nucleic acid synthesis, adsorption and protection.

This research endeavour is a collaborative project of the University of Vienna, the Centre de Recherche et d'Enseignement de Géosciences de l'Environnement (Aix-en-Provence) and the University of Bordeaux and is funded by the Austrian FWF and the French ANR.

Funded by FWF

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